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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZR1
All Species:
31.82
Human Site:
S305
Identified Species:
53.85
UniProt:
Q9UM11
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM11
NP_001129669.1
496
55179
S305
I
R
T
P
P
L
Q
S
E
R
R
L
Q
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117911
714
76643
S526
I
R
T
P
P
L
Q
S
E
R
R
L
Q
G
H
Dog
Lupus familis
XP_542177
493
54677
S305
I
R
T
P
P
L
Q
S
E
R
R
L
Q
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1K5
493
54670
S305
I
R
T
P
P
L
Q
S
E
R
R
L
Q
G
H
Rat
Rattus norvegicus
Q62623
499
54810
V302
V
R
V
A
E
H
H
V
A
T
L
S
G
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515034
292
32361
G104
Q
I
W
D
A
A
A
G
K
K
L
S
M
L
E
Chicken
Gallus gallus
NP_989485
495
55111
W305
I
R
T
P
P
L
K
W
E
G
G
F
Q
G
N
Frog
Xenopus laevis
NP_001080659
493
54681
S305
I
R
T
P
P
V
Q
S
E
R
R
L
Q
G
H
Zebra Danio
Brachydanio rerio
NP_956547
495
54963
S307
I
R
T
P
P
L
Q
S
E
R
R
L
Q
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524852
478
53489
S290
T
R
T
P
Q
L
Q
S
E
R
R
L
A
G
H
Honey Bee
Apis mellifera
XP_623291
486
54195
S298
V
R
T
P
C
V
V
S
E
R
R
L
G
A
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188191
1356
151017
S994
C
E
D
R
R
M
V
S
P
Q
K
V
K
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L3Z8
483
52822
K295
C
Q
E
D
H
V
S
K
L
A
G
H
K
S
E
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
M332
L
V
E
I
Y
D
V
M
K
R
K
C
I
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69
98.1
N.A.
97.7
37.6
N.A.
58.4
91.5
95.3
91.7
N.A.
68.7
69.7
N.A.
29.3
Protein Similarity:
100
N.A.
69
98.9
N.A.
98.9
54.9
N.A.
58.8
94.1
98.1
95.1
N.A.
78.8
80.6
N.A.
32
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
0
60
93.3
100
N.A.
80
60
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
13.3
73.3
100
100
N.A.
80
73.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
38.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
56.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
8
8
0
8
8
0
0
8
8
0
% A
% Cys:
15
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
15
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
15
0
8
0
0
0
65
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
15
0
15
58
0
% G
% His:
0
0
0
0
8
8
8
0
0
0
0
8
0
8
58
% H
% Ile:
50
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
15
8
15
0
15
0
0
% K
% Leu:
8
0
0
0
0
50
0
0
8
0
15
58
0
8
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
0
65
50
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
8
0
50
0
0
8
0
0
50
0
0
% Q
% Arg:
0
72
0
8
8
0
0
0
0
65
58
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
8
65
0
0
0
15
0
8
8
% S
% Thr:
8
0
65
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
15
8
8
0
0
22
22
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _